产品货号：
Z20018
中文名称：
L1/ORF2抗体
英文名称：
Anti-L1/ORF2 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-L1/ORF2 Antibody |
| 指标别名 | LINE-1 retrotransposable element ORF2 protein;ORF2p;Reverse transcriptase;Endonuclease |
| 克隆性 | Polyclonal |
| 检验物种 | human,chimpanzee |
| 应用范围 | Dot blot,ELISA,WB |
| 基因名称 | LORF2 |
| 抗体来源 | Chicken |
| 抗体类型 | IgY |
| 免疫原 | This IgY fraction antibody was prepared from eggs of chickens laid after repeated immunizations with two synthetic peptides conjugated to keyhole limpet hemocyanin (KLH).?The peptides correspond to regions within the endonuclease domain of L1/ORF2 protein. |
| 计算分子量 | 23kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | L1/ORF2 Antibody is directed against two regions within the endonuclease domain of L1 ORF2 protein.This product is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above.??Reactivity occurs against human L1/ORF2 protein and is useful in determining its presence in various assays.?A BLAST analysis was used to suggest cross-reactivity with L1/ORF2 proteins from chimpanzee sources based on 100% homology with the immunizing sequences,and from macaque,fruit fly,cattle,dog,opossum,and rat sources based on 69～88% homology with the immunizing sequences. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.The L1 (LINE-1),or Long INterspersed Element,retrotransposon ORF2 is the most common open reading frame in the human genome,present in various forms in many thousands of copies.This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signaling.Both intact ORF1 and ORF2 are absolutely required for autonomous retro-transposition.ORF2 encodes an endonuclease,reverse transcriptase,and zinc knuckle domains.The expression of ORF2 appears to be tightly regulated except in germ line tissues,embryonic tissues,and certain cancers including teratomas,testicular cancers,and leukemias.This antibody is intended for use in studying control of L1 retrotransposons. |
| Uniprot ID | O00370 |
| 基因名全称 | Putative Dihydrofolate reductase |
| 推荐稀释比 | ELISA:1:10,000 WB:1:2,000-1_10,000 |
相关搜索：L1/ORF2抗体，ORF2多抗，Anti-L1/ORF2 Antibody